Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28784017 | 0.86 | MAPT (0.45) | MAPTMTNR1AMTNR1BTSHRALDH1A1 | |
| SCHEMBL11328313 | 0.81 | TSHR (0.46) | MAPTMTNR1AMTNR1BTSHRALDH1A1 | |
| SCHEMBL14313368 | 0.80 | MAPT (0.41) | MAPTMTNR1AMTNR1BTSHRALDH1A1 | |
| Propane SCHEMBL28029159 | 0.79 | MTNR1A (0.45) | MAPTMTNR1AMTNR1BTSHRALDH1A1 | |
| SCHEMBL2186074 | 0.79 | CA4 (0.42) | MAPTMTNR1AMTNR1BTSHRALDH1A1 | |
| SCHEMBL218320 | 0.79 | THRB (0.46) | MAPTMTNR1AMTNR1BTSHRALDH1A1 | |
| SCHEMBL1404301 | 0.79 | MTNR1A (0.42) | MAPTMTNR1AMTNR1BTSHRALDH1A1 | |
| SCHEMBL9780129 | 0.78 | MAPT (0.48) | MAPTMTNR1AMTNR1BTSHRALDH1A1 | |
| SCHEMBL11328324 | 0.78 | ALDH1A1 (0.51) | MAPTTSHRALDH1A1POLBPPARG | |
| Ammonia Solution, Strong SCHEMBL9245393 | 0.77 | LTA4H (0.40) | MAPTMTNR1AMTNR1BTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |
| EP-0730585-A1 | ETHERIFIED ALKYL OR ARYLCARBAMYLMETHYLATED AMINOTRIAZINES AND CURABLE COMPOSITIONS CONTAINING THE SAME | PPG INDUSTRIES, INC. (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5545696-A | FILM FORMERS IN COATINGS | PPG INDUSTRIES, INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5536835-A | Etherified alkyl or arylcarbamylmethylated aminotriazines and curable compositions containing the same | PPG INDUSTRIES, INC. (US) | 1996-07-16 | — | — | US | disclosed |
| WO-1995014677-A1 | ETHERIFIED ALKYL OR ARYLCARBAMYLMETHYLATED AMINOTRIAZINES AND CURABLE COMPOSITIONS CONTAINING THE SAME | PPG INDUSTRIES, INC. (US) | 1995-06-01 | — | — | WO | disclosed |