Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693598 | 0.92 | ELANE (0.35) | TSHRELANEMEN1USP2ABCB11 | |
| SCHEMBL6691069 | 0.86 | ADORA3 (0.33) | TSHRMEN1USP2ABCB11LMNA | |
| SCHEMBL6699152 | 0.85 | HDAC3 (0.35) | HDAC3HDAC1HDAC2TSHRELANE | |
| SCHEMBL6689036 | 0.83 | HDAC3 (0.34) | HDAC3HDAC1HDAC2TSHRELANE | |
| SCHEMBL6697798 | 0.83 | GAA (0.34) | HDAC3HDAC1HDAC2TSHRELANE | |
| SCHEMBL6699702 | 0.83 | HDAC3 (0.34) | HDAC3HDAC1HDAC2TSHRELANE | |
| SCHEMBL6695731 | 0.82 | HDAC3 (0.33) | HDAC3HDAC1HDAC2TSHRELANE | |
| SCHEMBL6693132 | 0.81 | TP53 (0.38) | TSHRSLC2A1LMNAMAPTPSEN1 | |
| SCHEMBL6691008 | 0.80 | TP53 (0.40) | TSHRSLC2A1LMNAMAPTPSEN1 | |
| SCHEMBL5361978 | 0.80 | HDAC3 (0.37) | HDAC3HDAC1HDAC2TSHRELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0959389-B1 | Diazodisulfone compound and radiation-sensitive resin composition | JSR CORP (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6143460-A | PHOTOACID GENERATOR PROVIDING IMPROVED PHOTORESIST RESOLUTION | JSR CORPORATION (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0959389-A1 | Diazodisulfone compound and radiation-sensitive resin composition | JSR Corporation (JP) | 1999-11-24 | — | — | EP | disclosed |