SCHEMBL66940

SCHEMBL66940

Brc1ccc(-c2ccccc2)c(-c2ccccc2)c1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
MAPK1 P28482 3/20 0.50
MAPT P10636 2/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
BACE1 P56817 1/20 0.36
ALOX5 P09917 1/20 0.35
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
FABP4 P15090 1/20 0.35
ANPEP P15144 2/20 0.35
IL1RN P18510 1/20 0.35
ERAP2 Q6P179 1/20 0.35
ERAP1 Q9NZ08 1/20 0.35
HSD17B10 Q99714 2/20 0.34
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
CYP2A6 P11509 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC2 Q92769 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4137800 0.84 ALDH1A1 (0.52) ALDH1A1MAPK1MAPTLMNAHTT
SCHEMBL30866153 0.84 ALDH1A1 (0.52) ALDH1A1MAPK1MAPTLMNAHTT
SCHEMBL1229278 0.81 ALDH1A1 (0.54) ALDH1A1MAPK1MAPTLMNAHTT
SCHEMBL30565749 0.81 ALDH1A1 (0.54) ALDH1A1MAPK1MAPTLMNAHTT
SCHEMBL1589565 0.80 CNR1 (0.43) ALDH1A1MAPK1MAPTHSD17B10HPGD
Water SCHEMBL2802893 0.79 ALDH1A1 (0.52) ALDH1A1MAPK1MAPTLMNAHTT
SCHEMBL9626051 0.78 BACE1 (0.48) ALDH1A1MAPK1BACE1ALOX5CRHBP
SCHEMBL17075458 0.78 ALDH1A1 (0.46) ALDH1A1MAPK1MAPTLMNAHTT
SCHEMBL608536 0.77 ALDH1A1 (0.50) ALDH1A1MAPK1MAPTLMNAHTT
SCHEMBL4363398 0.77 ALDH1A1 (0.54) ALDH1A1MAPK1MAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685351-B OLED main body material based on triptycene framework and preparation method and application thereof 中国科学院化学研究所 2023-04-18 CN claimed
CN-114685351-A OLED main body material based on triptycene framework and preparation method and application thereof 中国科学院化学研究所 2022-07-01 CN claimed
US-20090149675-A1 PROCESS FOR THE PREPARATION OF ARYL-DIAMINES XEROX CORPORATION (US) 2009-06-11 US claimed
US-7544842-B1 Process for the preparation of aryl-diamines XEROX CORPORATION (US) 2009-06-09 US claimed
US-12522697-B2 Polyarylene sulfide, and purification method and production method therefor DIC CORPORATION (JP) 2026-01-13 US disclosed
EP-4638547-A1 AROMATIC POLYMER, PROCESS FOR PRODUCING A POLYMER, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2025-10-29 EP disclosed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
WO-2025126850-A1 POLYARYLENE SULFIDE RESIN AND METHOD FOR PRODUCING ADSORPTION COLUMN DIC株式会社 2025-06-19 WO disclosed
CN-116601214-B Crosslinked polyarylene sulfide, composition, and process for producing molded article DIC株式会社 2024-11-12 CN disclosed
CN-116234862-B Crosslinked polyarylene sulfide, composition, and process for producing molded article DIC株式会社 2024-10-29 CN disclosed
CN-114729123-B Polyarylene sulfide, method for purifying same, and method for producing same DIC株式会社 2024-09-27 CN disclosed
US-20240059841-A1 CROSSLINKED POLYARYLENE SULFIDE, COMPOSITION, AND METHOD FOR PRODUCING MOLDED ARTICLE DIC CORPORATION (JP) 2024-02-22 US disclosed
EP-0489085-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1992-06-10 EP disclosed
EP-0401296-A4 RIGID-ROD POLYMERS MAXDEM INC (US) 1992-03-18 EP disclosed
US-5064569-A Liquid crystals, chirally tilted, phenyl carboxylates MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-11-12 US disclosed
WO-1991002764-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1991-03-07 WO disclosed
EP-0401296-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1990-12-12 EP disclosed
WO-1989007617-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1989-08-24 WO disclosed
EP-0260275-A1 OPTICALLY ACTIVE COMPOUNDS MERCK PATENT GmbH (DE) 1988-03-23 EP disclosed
WO-1987005017-A2 OPTICALLY ACTIVE COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1987-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149675-A1 PROCESS FOR THE PREPARATION OF ARYL-DIAMINES DDT, DDC, HDHD5 ALDH1A1 147/4885MAPK1 1553/4885MAPT 4320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.