Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28977231 | 1.00 | NOS2 (0.51) | NOS2PPARGGRIA1ALDH1A1CYP1A2 | |
| SCHEMBL6713032 | 1.00 | NOS2 (0.51) | NOS2PPARGGRIA1ALDH1A1CYP1A2 | |
| SCHEMBL6694861 | 1.00 | NOS2 (0.51) | NOS2PPARGGRIA1ALDH1A1CYP1A2 | |
| SCHEMBL30743600 | 0.96 | NOS2 (0.52) | NOS2PPARGGRIA1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL30743613 | 0.95 | NOS2 (0.51) | NOS2PPARGGRIA1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL27218454 | 0.95 | NOS2 (0.51) | NOS2PPARGGRIA1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL29179025 | 0.95 | NOS2 (0.51) | NOS2PPARGGRIA1ALDH1A1CYP1A2 | |
| Chloromethane SCHEMBL29179050 | 0.92 | ALDH1A1 (0.51) | NOS2PPARGGRIA1ALDH1A1CYP1A2 | |
| SCHEMBL5546193 | 0.90 | GRIA1 (0.52) | NOS2PPARGGRIA1MMP2MMP9 | |
| SCHEMBL26222748 | 0.86 | EGFR (0.59) | NOS2PPARGALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040048928-A1 | Novel amino acid compounds and photoprotecting compositions comprised thereof | L'OREAL (FR) | 2004-03-11 | — | — | US | claimed |
| EP-1278718-B1 | NOVEL AMINO ACID DERIVATIVES, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USES THEREOF AS SUNSCREENS | OREAL (FR) | 2003-12-17 | — | — | EP | claimed |
| US-6641802-B2 | Copper sulfat complexes to amino acid | SOCIETE L'OREAL S.A. (FR) | 2003-11-04 | — | — | US | claimed |
| EP-1278718-A1 | NOVEL AMINO ACID DERIVATIVES, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USES THEREOF AS SUNSCREENS | L'OREAL (FR) | 2003-01-29 | — | — | EP | claimed |
| US-20020150545-A1 | Novel amino acid compounds and photoprotecting compositions comprised thereof | L'OREAL (FR) | 2002-10-17 | — | — | US | claimed |
| WO-2001081297-A1 | NOVEL AMINO ACID DERIVATIVES, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USES THEREOF AS SUNSCREENS | L'OREAL (FR) | 2001-11-01 | — | — | WO | claimed |
| WO-2004098313-A1 | ACRYLAMIDE REDUCTION IN FOOD | RITTER HELMUT (DE) | 2004-11-18 | — | — | WO | disclosed |
| US-20040048928-A1 | Novel amino acid compounds and photoprotecting compositions comprised thereof | L'OREAL (FR) | 2004-03-11 | — | — | US | disclosed |
| EP-1278718-B1 | NOVEL AMINO ACID DERIVATIVES, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USES THEREOF AS SUNSCREENS | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6641802-B2 | Copper sulfat complexes to amino acid | SOCIETE L'OREAL S.A. (FR) | 2003-11-04 | — | — | US | disclosed |
| EP-1278718-A1 | NOVEL AMINO ACID DERIVATIVES, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USES THEREOF AS SUNSCREENS | L'OREAL (FR) | 2003-01-29 | — | — | EP | disclosed |
| US-20020150545-A1 | Novel amino acid compounds and photoprotecting compositions comprised thereof | L'OREAL (FR) | 2002-10-17 | — | — | US | disclosed |
| WO-2001081297-A1 | NOVEL AMINO ACID DERIVATIVES, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USES THEREOF AS SUNSCREENS | L'OREAL (FR) | 2001-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020150545-A1 | Novel amino acid compounds and photoprotecting compositions comprised thereof | PELP1, ALAD, CRY1 | NOS2 962/4885PPARG 3089/4885GRIA1 592/4885 |
| US-20040048928-A1 | Novel amino acid compounds and photoprotecting compositions comprised thereof | PELP1, ALAD, CRY1 | NOS2 962/4885PPARG 3089/4885GRIA1 592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.