Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694321 | 0.88 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19MCHR1TSHR | |
| SCHEMBL6690278 | 0.83 | CYP1A2 (0.35) | CYP1A2CYP2C9CYP2C19MCHR1TSHR | |
| SCHEMBL6694292 | 0.80 | CYP1A2 (0.36) | CYP1A2CYP2C9CYP2C19MCHR1TSHR | |
| SCHEMBL6697773 | 0.79 | LMNA (0.35) | CYP1A2CYP2C9CYP2C19TP53DRD2 | |
| SCHEMBL6696724 | 0.75 | ALDH1A1 (0.35) | HSD17B10GAAKDM4EALDH1A1ALOX15 | |
| SCHEMBL6697887 | 0.73 | HRH3 (0.33) | CYP1A2CYP2C9CYP2C19TSHRGAA | |
| SCHEMBL6698691 | 0.73 | HTR2A (0.33) | CYP1A2CYP2C9CYP2C19TSHRGAA | |
| SCHEMBL6697903 | 0.73 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19MCHR1TSHR | |
| SCHEMBL6690660 | 0.71 | HSD11B1 (0.35) | HSD17B10GAAKDM4EALDH1A1GLA | |
| SCHEMBL6691559 | 0.71 | ALDH1A1 (0.34) | TSHRHSD17B10GAAALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0890605-A2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |