Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693173 | 0.86 | HSD11B1 (0.35) | HSD11B1DRD2MAPK1SMN1; SMN2DRD3 | |
| SCHEMBL6694321 | 0.84 | CYP1A2 (0.39) | ALDH1A1GAAHPGDALOX15HSD17B10 | |
| SCHEMBL6697805 | 0.78 | AADAT (0.32) | AADAT | |
| SCHEMBL6690587 | 0.74 | ABCB1 (0.40) | ALDH1A1 | |
| SCHEMBL6694906 | 0.71 | CYP1A2 (0.36) | ALDH1A1GAAHPGDALOX15HSD17B10 | |
| SCHEMBL6692263 | 0.69 | ALDH1A1 (0.35) | ALDH1A1GAAALOX15HSD17B10KDM4E | |
| SCHEMBL6697903 | 0.67 | CYP1A2 (0.38) | ALDH1A1GAAHPGDALOX15HSD17B10 | |
| SCHEMBL6690997 | 0.67 | MGLL (0.33) | — | |
| SCHEMBL6694243 | 0.66 | HRH3 (0.35) | ALDH1A1HPGDALOX15HSD17B10KDM4E | |
| SCHEMBL6693448 | 0.63 | ABCB1 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |