Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.56 |
| ▸ | GPX4 | P36969 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | POLQ | O75417 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378758 | 0.87 | RAB9A (0.56) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL18200116 | 0.86 | POLQ (0.52) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL14577832 | 0.85 | ALDH1A1 (0.55) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL10454094 | 0.85 | ALDH1A1 (0.48) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL13164569 | 0.85 | ALDH1A1 (0.51) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL11704247 | 0.85 | ALDH1A1 (0.55) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL7711085 | 0.84 | ALDH1A1 (0.53) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL9660333 | 0.83 | ALDH1A1 (0.50) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL24832966 | 0.83 | TSPO (0.47) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL2085399 | 0.82 | MTNR1A (0.49) | ALDH1A1RAB9ANPC1PAX8GPX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |