Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072684 | 0.82 | F2 (0.39) | F2POLBMEN1TP53KMT2A | |
| Hydrochloric Acid SCHEMBL11057705 | 0.81 | F2 (0.38) | F2POLBMEN1TP53KMT2A | |
| SCHEMBL11139029 | 0.81 | ALDH1A1 (0.39) | HSD17B10ESR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6694938 | 0.77 | OPRM1 (0.42) | F2MTNR1BMTNR1AMEN1TP53 | |
| SCHEMBL10906692 | 0.76 | MEN1 (0.39) | ESR1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL10903886 | 0.75 | LMNA (0.36) | HSD17B10POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6695226 | 0.73 | F2 (0.46) | HSD17B10CTSDF2MTNR1BMTNR1A | |
| SCHEMBL10907705 | 0.72 | KMT2A (0.36) | ESR1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11057149 | 0.71 | CACNA1C (0.38) | MTNR1ASMN1; SMN2MEN1TP53KMT2A | |
| SCHEMBL10855153 | 0.71 | HTT (0.40) | HSD17B10POLBSMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3553083-B2 | — | — | 2004-08-11 | — | — | JP | claimed |
| EP-0852494-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-15 | — | — | EP | claimed |
| WO-1997009973-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-03-20 | — | — | WO | claimed |