Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689412 | 0.84 | MAPT (0.56) | POLBMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL29506302 | 0.71 | MEN1 (0.47) | POLBMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL28393245 | 0.71 | MEN1 (0.47) | POLBMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL29506268 | 0.69 | GAA (0.70) | POLBMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL3712068 | 0.66 | RAB9A (0.67) | POLBMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL15573286 | 0.63 | POLB (1.00) | POLBMAPTMAPK1LMNANPSR1 | |
| SCHEMBL29111450 | 0.62 | ACHE (0.54) | POLBMAPTNPC1RAB9AMAPK1 | |
| SCHEMBL30646329 | 0.62 | ACHE (0.54) | POLBMAPTNPC1RAB9AMAPK1 | |
| SCHEMBL4138642 | 0.62 | HTT (0.68) | POLBMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL19690945 | 0.62 | POLB (0.63) | POLBMAPTL3MBTL1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | claimed |