Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL28230352 | 0.92 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL1764151 | 0.92 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL1764063 | 0.91 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL824071 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL26128842 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL1520510 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL672369 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL7919473 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL1812517 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL528358 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981758-A | Thermally responsive brush polymers having a copolymer backbone and copolymer arms | 英菲诺姆国际有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-112876376-B | Synthesis method of allyl aryl compound | 山东领海生物科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-112876376-A | Synthesis method of allyl aryl compound | 山东领海生物科技有限公司 | 2021-06-01 | — | — | CN | disclosed |
| EP-3056542-B1 | (METH)ACRYLIC COPOLYMER, RESIN COMPOSITION, AND MOLDED PRODUCT OF SAID RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2018-11-28 | — | — | EP | disclosed |
| EP-3056542-A1 | (METH)ACRYLIC COPOLYMER, RESIN COMPOSITION, AND MOLDED PRODUCT OF SAID RESIN COMPOSITION | Mitsubishi Gas Chemical Company, Inc. (JP) | 2016-08-17 | — | — | EP | disclosed |
| CN-105008469-A | Latex emulsions and coating compositions prepared from latex emulsions | AKZO NOBEL COATINGS INT BV | 2015-10-28 | — | — | CN | disclosed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |
| CN-1296053-C | Use of non-digestible polymeric foams to sequester ingested materials thereby inhibiting their absorption by body | PROCTER & GAMBLE (US) | 2007-01-24 | — | — | CN | disclosed |
| US-20040192780-A1 | Alkylaminoalkyl-terminated sulfide/sulfonyl-containing propargyl amino-diol compounds for treatment of hypertension | G.D. SEARLE & CO. | 2004-09-30 | — | — | US | disclosed |
| CN-1531437-A | Use of non-digestible polymeric foams to sequester ingested materials thereby inhibiting their absorption by body | — | 2004-09-22 | — | — | CN | disclosed |
| WO-1993025574-A1 | INHIBITORS OF ANGIOTENSIN I CHYMASE(S) INCLUDING HUMAN HEART CHYMASE | PFIZER INC. (US) | 1993-12-23 | — | — | WO | disclosed |
| EP-0572909-A1 | Amino acid derivatives as renin inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 1993-12-08 | — | — | EP | disclosed |
| US-5258362-A | Enzyme inhibitors, amides with oxetane ring | ABBOTT LABORATORIES (US) | 1993-11-02 | — | — | US | disclosed |
| WO-1992022313-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-12-23 | — | — | WO | disclosed |
| EP-0509354-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-21 | — | — | EP | disclosed |
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |
| WO-1990002144-A1 | COMPOSITIONS FOR MAKING IMPROVED GAS PERMEABLE CONTACT LENSES | FUSED KONTACTS OF CHICAGO, INC. (US) | 1990-03-08 | — | — | WO | disclosed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192780-A1 | Alkylaminoalkyl-terminated sulfide/sulfonyl-containing propargyl amino-diol compounds for treatment of hypertension | REN, AGTR1, AGTR2 | ALDH1A1 720/4885MAPK1 1156/4885L3MBTL1 2447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.