Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.43 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701311 | 0.89 | KMT2A (0.45) | LMNATP53ALDH1A1KMT2AHPGD | |
| SCHEMBL5567749 | 0.88 | KMT2A (0.57) | POLBTP53ALDH1A1KMT2AHPGD | |
| SCHEMBL6701730 | 0.88 | KMT2A (0.48) | LMNATP53ALDH1A1KMT2AHPGD | |
| SCHEMBL6699164 | 0.86 | KMT2A (0.47) | ALDH1A1KMT2AHPGDOPRD1MAOB | |
| SCHEMBL6693686 | 0.86 | KMT2A (0.49) | ALDH1A1KMT2AHPGDOPRD1MAOB | |
| SCHEMBL6696335 | 0.85 | ALDH1A1 (0.49) | LMNATP53ALDH1A1KMT2AHPGD | |
| SCHEMBL6700031 | 0.85 | KMT2A (0.46) | HTTLMNAALDH1A1KMT2AHPGD | |
| SCHEMBL6701820 | 0.85 | ALDH1A1 (0.50) | POLBLMNATP53ALDH1A1KMT2A | |
| SCHEMBL6698658 | 0.84 | KMT2A (0.50) | LMNATP53ALDH1A1KMT2AHPGD | |
| SCHEMBL6702347 | 0.83 | OPRD1 (0.44) | LMNATP53ALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235855-A1 | Phospholipase C inhibitors for use in treating inflammatory disorders | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-11-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235855-A1 | Phospholipase C inhibitors for use in treating inflammatory disorders | PLA2G4C, PLA2G4B, PLA2G5 | POLB 2032/4885HTT 4808/4885LMNA 1355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.