Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | FCER2 | P06734 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692769 | 1.00 | MAPK1 (0.47) | MAPK1L3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL6678568 | 1.00 | MAPK1 (0.47) | MAPK1L3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL6633683 | 1.00 | MAPK1 (0.47) | MAPK1L3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL6691808 | 1.00 | MAPK1 (0.47) | MAPK1L3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL6696836 | 1.00 | MAPK1 (0.47) | MAPK1L3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL6629058 | 1.00 | MAPK1 (0.47) | MAPK1L3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL6650551 | 1.00 | MAPK1 (0.47) | MAPK1L3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL6694652 | 1.00 | MAPK1 (0.47) | MAPK1L3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL6062085 | 0.83 | ALOX15 (0.39) | ALOX15TSHRCASP1ALDH1A1 | |
| SCHEMBL6062091 | 0.83 | ALOX15 (0.39) | ALOX15TSHRCASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142999-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142999-A1 | Novel compounds and compositions as cathepsin inhibitors | CTSS, CTSB, CTSE | MAPK1 3715/4885L3MBTL1 4113/4885HPGD 1645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.