Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833436 | 0.90 | GAA (0.53) | ARPOLBGAACYP11B1CYP11B2 | |
| SCHEMBL6694769 | 0.88 | GAA (0.53) | ARGAAMEN1KMT2AMAPT | |
| SCHEMBL29559694 | 0.79 | KDM4E (0.53) | ARKDM4EUSP2ALDH1A1PGR | |
| SCHEMBL2596435 | 0.79 | KDM4E (0.53) | ARKDM4EUSP2ALDH1A1PGR | |
| SCHEMBL15832074 | 0.76 | POLB (0.51) | ARPOLBGAACYP11B1CYP11B2 | |
| SCHEMBL15832052 | 0.76 | SLC22A12 (0.52) | ARPOLBGAA | |
| SCHEMBL627816 | 0.72 | ALDH1A1 (0.52) | ARPOLBGAANQO1KDM4E | |
| SCHEMBL2539990 | 0.72 | CYP11B1 (0.58) | ARPOLBGAACYP11B1CYP11B2 | |
| SCHEMBL23163257 | 0.72 | BCAT2 (0.50) | ARKDM4EUSP2ALDH1A1 | |
| SCHEMBL24824091 | 0.72 | AR (0.51) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029735-A1 | Substituted herbicidal phenyluracils | ANDREE ROLAND (DE) | 2004-02-12 | — | — | US | disclosed |
| US-6624120-B1 | Such as 1-(4-cyano-2-fluoro-5-(6-methoxy-naphthalen-2-yl-oxy)-phenyl)-2,6-dioxo -1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029735-A1 | Substituted herbicidal phenyluracils | DDT, MTX1, MTX2 | AR 4347/4885POLB 1551/4885GAA 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.