Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitamide SCHEMBL5180724 | 1.00 | FAAH (0.47) | FAAHSOAT1MEN1TP53CYP1A2 | |
| Tetradecanamide SCHEMBL5182998 | 1.00 | FAAH (0.47) | FAAHSOAT1MEN1TP53CYP1A2 | |
| Stearic Acid SCHEMBL5183203 | 0.92 | PLA2G2A (0.55) | MEN1KMT2APLA2G2APLA2G4AALDH1A1 | |
| Acetic Acid SCHEMBL2905260 | 0.90 | EPHX1 (0.55) | FAAHMEN1CYP1A2KMT2AEPHX1 | |
| Dodine SCHEMBL9766434 | 0.90 | EPHX1 (0.55) | FAAHMEN1CYP1A2KMT2AEPHX1 | |
| Dodine SCHEMBL22124 | 0.90 | EPHX1 (0.55) | FAAHMEN1CYP1A2KMT2AEPHX1 | |
| Acetic Acid SCHEMBL2905199 | 0.90 | EPHX1 (0.55) | FAAHMEN1CYP1A2KMT2AEPHX1 | |
| Acetic Acid SCHEMBL29256286 | 0.90 | EPHX1 (0.55) | FAAHMEN1CYP1A2KMT2AEPHX1 | |
| Dodine SCHEMBL9055972 | 0.90 | EPHX1 (0.55) | FAAHMEN1CYP1A2KMT2AEPHX1 | |
| Acetic Acid SCHEMBL3289314 | 0.90 | EPHX1 (0.55) | FAAHMEN1CYP1A2KMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500536-B | Hair cosmetic | LION CORP. (JP) | 2011-12-28 | — | — | CN | disclosed |
| CN-101500536-A | Hair cosmetic | LION CORP (JP) | 2009-08-05 | — | — | CN | disclosed |
| CN-1250194-C | External preparation | LION CORP (JP) | 2006-04-12 | — | — | CN | disclosed |
| CN-1568173-A | External preparation | LION CORP (JP) | 2005-01-19 | — | — | CN | disclosed |
| US-20040092599-A1 | Production process of guanidine derivative containing amido group and salt thereof | AJINOMOTO CO., INC. (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1270552-A2 | Production process for a guanidine derivative containing an amido group and for a salt thereof | Ajinomoto Co., Inc. (JP) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092599-A1 | Production process of guanidine derivative containing amido group and salt thereof | FASN, GMPS, CEL | FAAH 278/4885SOAT1 166/4885MEN1 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.