Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709375 | 0.89 | ALDH1A1 (0.73) | ALDH1A1CYP3A4IDH1MIFPRKDC | |
| SCHEMBL5430015 | 0.86 | ALDH1A1 (0.59) | ALDH1A1CYP3A4IDH1MIFCYP4F2 | |
| SCHEMBL22678650 | 0.86 | ALDH1A1 (0.70) | ALDH1A1CYP3A4IDH1 | |
| SCHEMBL16154053 | 0.86 | ALDH1A1 (0.63) | ALDH1A1CYP3A4IDH1MIF | |
| SCHEMBL5437580 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CYP3A4IDH1MIFPRKDC | |
| SCHEMBL7671543 | 0.82 | ALDH1A1 (0.63) | ALDH1A1CYP3A4IDH1MIFCYP4F2 | |
| SCHEMBL7671540 | 0.82 | ALDH1A1 (0.63) | ALDH1A1CYP3A4IDH1MIFPRKDC | |
| SCHEMBL801397 | 0.82 | ALDH1A1 (0.63) | ALDH1A1CYP3A4IDH1MIFPRKDC | |
| SCHEMBL14233717 | 0.82 | LMNA (0.45) | KAT6A | |
| SCHEMBL6693082 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |