Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | LPL | P06858 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13034148 | 0.89 | ALDH1A1 (0.58) | ALDH1A1NAAACYP3A4THRBPLK1 | |
| SCHEMBL132773 | 0.87 | ALDH1A1 (0.78) | ALDH1A1CYP3A4POLBKDM4EL3MBTL1 | |
| SCHEMBL13783906 | 0.87 | ALDH1A1 (0.56) | ALDH1A1CYP3A4THRBKDM4EESR1 | |
| SCHEMBL13783933 | 0.85 | ALDH1A1 (0.59) | ALDH1A1CYP3A4THRBKDM4ELPL | |
| SCHEMBL4242570 | 0.84 | ALDH1A1 (0.62) | ALDH1A1CYP3A4KDM4EESR1ESR2 | |
| SCHEMBL10017478 | 0.83 | ALDH1A1 (0.67) | ALDH1A1NAAACYP3A4PLK1POLB | |
| SCHEMBL24966607 | 0.82 | ALDH1A1 (0.60) | ALDH1A1CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL27654043 | 0.82 | ALDH1A1 (0.60) | ALDH1A1CYP3A4POLBKDM4EMEN1 | |
| SCHEMBL13783931 | 0.82 | THRB (0.46) | ALDH1A1NAAATHRBPLK1POLB | |
| SCHEMBL6696949 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018093-B2 | Hemiasterlin derivatives and antibody-drug conjugates including same | Sumitomo Pharma Co., Ltd. (JP) | 2024-06-25 | — | — | US | disclosed |
| US-7563917-B2 | Silicon compound and a production process for silicon compound | CHISSO CORPORATION (JP) | 2009-07-21 | — | — | US | disclosed |
| US-20070004932-A1 | Silicon compound and a production process for silicon compound | JNC CORPORATION (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004932-A1 | Silicon compound and a production process for silicon compound | STS, SMS, SRM | ALDH1A1 1549/4885NAAA 1531/4885CYP3A4 919/4885 |
| US-12018093-B2 | Hemiasterlin derivatives and antibody-drug conjugates including same | FCGRT, QARS1, INHA | ALDH1A1 1215/4885NAAA 1701/4885CYP3A4 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.