Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073311 | 0.84 | CYP3A4 (0.33) | CYP3A4CYP1A2ALDH1A1TSHRLMNA | |
| SCHEMBL10341191 | 0.80 | CYP3A4 (0.35) | CYP3A4POLBPLA2G7CYP1A1CYP1A2 | |
| SCHEMBL10341257 | 0.78 | LMNA (0.36) | CYP3A4CYP1A2ALDH1A1TSHRLMNA | |
| SCHEMBL12985905 | 0.77 | LMNA (0.35) | CYP3A4CYP1A2ALDH1A1MAPK1S1PR1 | |
| SCHEMBL9420713 | 0.77 | LMNA (0.33) | CYP3A4S1PR1LMNA | |
| SCHEMBL6357268 | 0.77 | POLB (0.41) | CYP3A4POLBCD44ALDH1A1SMN1; SMN2 | |
| SCHEMBL12360639 | 0.74 | HTR2A (0.37) | CYP3A4S1PR1LMNA | |
| SCHEMBL6414355 | 0.74 | ALDH1A1 (0.45) | CYP3A4CD44ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL31568962 | 0.74 | CYP3A4 (0.48) | CYP3A4POLBPLA2G7CD44ALDH1A1 | |
| SCHEMBL345826 | 0.74 | CYP3A4 (0.48) | CYP3A4POLBPLA2G7CD44ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068789-B | The method of position chlorination alkyl benzene amine between selectivity | LONZA LTD. (CH) | 2015-11-25 | — | — | CN | disclosed |
| US-9193667-B2 | Process for the selective meta-chlorination of alkylanilines | LONZA LTD. (CH) | 2015-11-24 | — | — | US | disclosed |
| US-20130338400-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | LONZA LTD. (CH) | 2013-12-19 | — | — | US | disclosed |
| EP-2606028-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | Lonza Ltd (CH) | 2013-06-26 | — | — | EP | disclosed |
| CN-103068789-A | Process for the selective meta-chlorination of alkylanilines | LONZA AG | 2013-04-24 | — | — | CN | disclosed |
| WO-2012022460-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | LONZA LTD (CH) | 2012-02-23 | — | — | WO | disclosed |
| US-4950792-A | CHAIN LENGTHENING, CROSSLINKING AGENT FOR POLYURETHANES | LONZA LTD. (CH) | 1990-08-21 | — | — | US | disclosed |
| EP-0220641-B1 | SUBSTITUTED P,P'-METHYLENE-BIS-ANILINES | LONZA AG (CH) | 1990-02-28 | — | — | EP | disclosed |
| EP-0220641-A1 | Substituted p,p'-methylene-bis-anilines | LONZA AG (CH) | 1987-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338400-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | CLIC4, CLIC1, NPM1 | CYP3A4 54/4885POLB 1303/4885PLA2G7 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.