Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697059 | 0.92 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL6612972 | 0.89 | HPGD (0.53) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL6624267 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL6623939 | 0.87 | TSHR (0.54) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL6625785 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL20899670 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL3613938 | 0.79 | HSD11B1 (0.50) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL5831433 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL5830810 | 0.78 | AKT1 (0.57) | ALDH1A1MAPTKMT2AMEN1TSHR | |
| SCHEMBL3253320 | 0.77 | HSD11B1 (0.50) | ALDH1A1MAPTHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112779-A1 | NEW USE VII | BIOVITRUM AB (SE) | 2004-12-29 | — | — | WO | disclosed |
| US-20030130279-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130279-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | HSD11B1, HSD17B1, HSD3B1 | ALDH1A1 47/4885MAPT 3254/4885HPGD 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.