Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701834 | 0.84 | TSHR (0.47) | OPRD1ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL6698150 | 0.83 | NPSR1 (0.51) | OPRD1ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL5568912 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KMT2ANPSR1MEN1HPGD | |
| SCHEMBL6883992 | 0.81 | NPSR1 (0.50) | OPRD1ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL6702360 | 0.80 | HTT (0.48) | NPSR1 | |
| SCHEMBL6701730 | 0.80 | KMT2A (0.48) | OPRD1ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL5568497 | 0.80 | OPRD1 (0.49) | OPRD1ALDH1A1KMT2AOPRM1MEN1 | |
| SCHEMBL29968772 | 0.80 | OPRD1 (0.49) | OPRD1ALDH1A1KMT2AOPRM1MEN1 | |
| SCHEMBL6699164 | 0.79 | KMT2A (0.47) | OPRD1ALDH1A1KMT2AOPRM1MEN1 | |
| SCHEMBL6693686 | 0.79 | KMT2A (0.49) | OPRD1ALDH1A1KMT2AOPRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235855-A1 | Phospholipase C inhibitors for use in treating inflammatory disorders | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-11-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235855-A1 | Phospholipase C inhibitors for use in treating inflammatory disorders | PLA2G4C, PLA2G4B, PLA2G5 | OPRD1 1606/4885ALDH1A1 1583/4885KMT2A 4455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.