Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.43 |
| ▸ | QDPR | P09417 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 4/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.42 |
| ▸ | DRD1 | P21728 | 3/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8528751 | 0.85 | SLC18A3 (0.69) | HTR2CSIGMAR1SLC18A3NAMPTJAK3 | |
| Trifluoroacetic Acid SCHEMBL6703422 | 0.85 | HTR2C (0.51) | HTR2CSIGMAR1SLC18A3P2RY14ITGB3 | |
| Trifluoroacetic Acid SCHEMBL2303613 | 0.84 | HTR2C (0.78) | HTR2CSIGMAR1SLC18A3P2RY14DRD5 | |
| SCHEMBL2266245 | 0.83 | SLC18A3 (0.61) | HTR2CSIGMAR1SLC18A3QDPRNAMPT | |
| Trifluoroacetic Acid SCHEMBL3031403 | 0.81 | PRKAB2 (0.44) | SLC18A3ITGB3 | |
| Trifluoroacetic Acid SCHEMBL26600330 | 0.81 | HTR2C (0.54) | HTR2CSIGMAR1SLC18A3P2RY14ITGB3 | |
| Hydrochloric Acid SCHEMBL1203533 | 0.81 | SLC18A3 (0.59) | HTR2CSIGMAR1SLC18A3QDPRNAMPT | |
| Trifluoroacetic Acid SCHEMBL942293 | 0.81 | EPHX1 (0.52) | HTR2CSIGMAR1SLC18A3P2RY14ITGB3 | |
| Trifluoroacetic Acid SCHEMBL381669 | 0.80 | SLC18A3 (0.51) | HTR2CSIGMAR1SLC18A3HTR1ASLC6A2 | |
| Trifluoroacetic Acid SCHEMBL31700691 | 0.79 | HTR2C (0.48) | HTR2CSIGMAR1SLC18A3P2RY14ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044008-A1 | Use of therapeutic benzamide derivatives | DAUGAN ALAIN CLAUDE-MARIE (FR) | 2004-03-04 | — | — | US | disclosed |
| EP-1286670-A2 | USE OF THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001097810-A2 | USE OF THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044008-A1 | Use of therapeutic benzamide derivatives | MTTP, LIPC, CETP | HTR2C 2767/4885SIGMAR1 1346/4885SLC18A3 1513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.