Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8528751 | 0.87 | SLC18A3 (0.69) | SLC18A3SIGMAR1HTR2CNAMPTJAK3 | |
| SCHEMBL949252 | 0.87 | SLC18A3 (0.68) | SLC18A3SIGMAR1HTR2CHTR1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL31615878 | 0.85 | SLC18A3 (0.66) | SLC18A3SIGMAR1HTR2CHTR1ASLC6A2 | |
| Trifluoroacetic Acid SCHEMBL942293 | 0.84 | EPHX1 (0.52) | SLC18A3SIGMAR1HTR2CHTR1ASLC6A2 | |
| Trifluoroacetic Acid SCHEMBL6698285 | 0.80 | HTR2C (0.54) | SLC18A3SIGMAR1HTR2CHTR1ASLC6A2 | |
| Trifluoroacetic Acid SCHEMBL2303613 | 0.80 | HTR2C (0.78) | SLC18A3SIGMAR1HTR2CHTR1ASLC6A2 | |
| Trifluoroacetic Acid SCHEMBL6703422 | 0.77 | HTR2C (0.51) | SLC18A3SIGMAR1HTR2CHTR1ASLC6A2 | |
| Trifluoroacetic Acid SCHEMBL21381947 | 0.77 | HTR2C (0.50) | HTR2CJAK3 | |
| Hydrochloric Acid SCHEMBL31615877 | 0.77 | HTR2C (0.81) | SLC18A3SIGMAR1HTR2CHTR1ASLC6A2 | |
| Trifluoroacetic Acid SCHEMBL26600330 | 0.77 | HTR2C (0.54) | SLC18A3SIGMAR1HTR2CHTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096524-B2 | Anthelmintic agents and their use | INTERVET INTERNATIONAL B.V. (NL) | 2015-08-04 | — | — | US | disclosed |
| EP-2408742-B1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INT BV (NL) | 2014-09-03 | — | — | EP | disclosed |
| EP-2408742-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-01-25 | — | — | EP | disclosed |
| US-20110319393-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2011-12-29 | — | — | US | disclosed |
| WO-2010115688-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319393-A1 | ANTHELMINTIC AGENTS AND THEIR USE | ACHE, ABCB11, MPO | SLC18A3 2405/4885SIGMAR1 4049/4885HTR2C 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.