Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8528751

O=C(O)C(F)(F)F.c1ccc(C2CCNCC2)cc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 2/20 0.69
SIGMAR1 Q99720 1/20 0.69
HTR2C P28335 8/20 0.54
NAMPT P43490 1/20 0.47
JAK3 P52333 1/20 0.47
KDM1A O60341 1/20 0.46
HPGD P15428 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HTR6 P50406 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL381669 0.87 SLC18A3 (0.51) SLC18A3SIGMAR1HTR2CNAMPTJAK3
Trifluoroacetic Acid SCHEMBL2303613 0.85 HTR2C (0.78) SLC18A3SIGMAR1HTR2CKDM1A
Trifluoroacetic Acid SCHEMBL6698285 0.85 HTR2C (0.54) SLC18A3SIGMAR1HTR2CNAMPTJAK3
Trifluoroacetic Acid SCHEMBL26600330 0.85 HTR2C (0.54) SLC18A3SIGMAR1HTR2CKDM1A
Trifluoroacetic Acid SCHEMBL21523769 0.85 HTR2C (0.56) SLC18A3SIGMAR1HTR2CHTR6
SCHEMBL9400647 0.84 SLC18A3 (0.77) SLC18A3SIGMAR1HTR2CNAMPTJAK3
Trifluoroacetic Acid SCHEMBL16755914 0.84 CYP11B2 (0.50) SLC18A3SIGMAR1HTR2CKDM1AKMT2A
SCHEMBL4574 0.83 SLC18A3 (1.00) SLC18A3SIGMAR1HTR2CHPGDKMT2A
Benzene SCHEMBL28128069 0.83 SLC18A3 (1.00) SLC18A3SIGMAR1HTR2CHPGDKMT2A
Trifluoroacetic Acid SCHEMBL6703422 0.83 HTR2C (0.51) SLC18A3SIGMAR1HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648130-B1 RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING UNIV MICHIGAN (US) 1998-12-30 EP disclosed
EP-0648130-A1 RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING THE UNIVERSITY OF MICHIGAN (US) 1995-04-19 EP disclosed
EP-0648130-A4 RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING. UNIV MICHIGAN (US) 1994-01-26 EP disclosed
US-5077035-A Scintigraphic imaging of brain; Alzheimer*s diagnosis THE UNIVERSITY OF MICHIGAN (US) 1991-12-31 US disclosed
WO-1991017776-A1 RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING THE UNIVERSITY OF MICHIGAN (US) 1991-11-28 WO disclosed