Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | RAB9A | P51151 | 9/20 | 0.63 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | NPC1 | O15118 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.63 |
| ▸ | RELA | Q04206 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44869 | 0.82 | ALDH1A1 (1.00) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| Bromide SCHEMBL7128948 | 0.80 | ALDH1A1 (0.96) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| Bromide SCHEMBL5325472 | 0.78 | ALDH1A1 (1.00) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5450269 | 0.78 | ALDH1A1 (0.92) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL2907964 | 0.78 | ALDH1A1 (1.00) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL11505502 | 0.76 | ALDH1A1 (0.79) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL1068291 | 0.74 | MAPT (0.97) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| Bromide SCHEMBL8359253 | 0.73 | MAPT (1.00) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL426369 | 0.73 | MAPT (0.66) | ALDH1A1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL8124240 | 0.73 | MAPT (0.66) | ALDH1A1RAB9AMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | ALDH1A1 925/4885RAB9A 2032/4885MAPT 3376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.