Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5533097 | 0.78 | PDE4A (0.38) | THRBALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL5531063 | 0.73 | MEN1 (0.36) | THRBSMN1; SMN2MAPTPOLBMEN1 | |
| SCHEMBL6699599 | 0.71 | IDO1 (0.57) | THRBALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL6579228 | 0.71 | TUBB4A (0.53) | ALDH1A1HTTSMN1; SMN2MAPTGAA | |
| SCHEMBL8804492 | 0.69 | YES1 (0.54) | SMN1; SMN2MAPTGAAPOLBMEN1 | |
| SCHEMBL27728387 | 0.68 | POLB (0.72) | ALDH1A1HTTSMN1; SMN2MAPTPOLB | |
| SCHEMBL2932649 | 0.68 | THRB (0.58) | THRBSMN1; SMN2MAPTGAAPOLB | |
| SCHEMBL8805633 | 0.68 | YES1 (0.68) | MAPTPOLBMEN1KMT2APDE4A | |
| SCHEMBL17195555 | 0.68 | HDAC6 (0.57) | ALDH1A1HTTSMN1; SMN2MAPTGAA | |
| SCHEMBL1684129 | 0.67 | POLB (0.42) | MAPTPOLBMEN1KMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004098605-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PDE4 INHIBITOR AND IL-1 TRAP | ALTANA PHARMA AG (DE) | 2004-11-18 | — | — | WO | disclosed |