Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531063 | 0.94 | MEN1 (0.36) | PDE4APDE4BPDE4CPDE4DTHRB | |
| SCHEMBL14972859 | 0.82 | CNR1 (0.34) | KDM4ENFATC1GSK3BDYRK1AALDH1A1 | |
| SCHEMBL6699595 | 0.78 | THRB (0.47) | PDE4APDE4BPDE4CPDE4DTHRB | |
| SCHEMBL6475849 | 0.77 | MMP13 (0.36) | THRBMAPTPOLBKDM4EPKM | |
| SCHEMBL6482645 | 0.75 | OPRD1 (0.35) | MAPTPOLBKDM4EPKMALDH1A1 | |
| SCHEMBL6579228 | 0.69 | TUBB4A (0.53) | MAPTSMN1; SMN2LMNAPOLBKDM4E | |
| SCHEMBL3850606 | 0.67 | TUBB4A (0.55) | PDE4APDE4BPDE4CPDE4DTHRB | |
| SCHEMBL3847520 | 0.66 | TUBB4A (0.56) | PDE4APDE4BPDE4CPDE4DTHRB | |
| SCHEMBL6475851 | 0.66 | MAPK14 (0.39) | THRBMAPTLMNAPOLBKDM4E | |
| SCHEMBL7057720 | 0.65 | THRB (0.59) | THRBMAPTSMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809279-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2007-07-25 | — | — | EP | claimed |
| WO-2006052712-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2006-05-18 | — | — | WO | claimed |