Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5533097 | 0.94 | PDE4A (0.38) | LMNASMN1; SMN2NFATC1GSK3BDYRK1A | |
| SCHEMBL14972859 | 0.87 | CNR1 (0.34) | NFATC1GSK3BDYRK1ASERPINE1KDM4E | |
| SCHEMBL6482645 | 0.77 | OPRD1 (0.35) | MAPTMDM2KDM4EPKMPOLB | |
| SCHEMBL6475849 | 0.76 | MMP13 (0.36) | MEN1KMT2ATHRBMAPTKDM4E | |
| SCHEMBL6699595 | 0.73 | THRB (0.47) | MEN1KMT2ASMN1; SMN2THRBMAPT | |
| SCHEMBL6579228 | 0.68 | TUBB4A (0.53) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL3845545 | 0.66 | TUBB4A (0.55) | MEN1KMT2ANFATC1GSK3BDYRK1A | |
| SCHEMBL6475851 | 0.64 | MAPK14 (0.39) | LMNATHRBMAPTKDM4EPKM | |
| SCHEMBL6474711 | 0.63 | CYP19A1 (0.38) | PDE4A | |
| SCHEMBL14972905 | 0.63 | MAPT (0.42) | SMN1; SMN2MAPTMDM2KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809279-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2007-07-25 | — | — | EP | claimed |
| WO-2006052712-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2006-05-18 | — | — | WO | claimed |