SCHEMBL6699746

SCHEMBL6699746

O=C1CN=C(c2cccc(C3=NCC(=O)O3)c2)O1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.34
HPGD P15428 1/20 0.34
PSMB8 P28062 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
HTT P42858 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PGR P06401 1/20 0.30
MAPT P10636 2/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30
NISCH Q9Y2I1 1/20 0.30
PTPN1 P18031 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16516875 0.88 KMT2A (0.43) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL135941 0.86 SMN1; SMN2 (0.42) NPC1RAB9AHPGDSMN1; SMN2HTT
SCHEMBL31567418 0.84 NOTUM (0.47) NPC1RAB9AHPGDSMN1; SMN2MAPT
SCHEMBL15362398 0.84 RXRA (0.41) NPC1HPGDSMN1; SMN2HTTL3MBTL1
SCHEMBL10448419 0.84 NOTUM (0.47) PGRMAPTALDH1A1
SCHEMBL6135895 0.83 NPC1 (0.33) NPC1RAB9ASMN1; SMN2
SCHEMBL6694697 0.81 NPC1 (0.33) NPC1RAB9AHPGDPSMB8SMN1; SMN2
SCHEMBL5855957 0.80 GSTP1 (0.46) HPGDSMN1; SMN2MAPTMEN1KMT2A
SCHEMBL343082 0.78 DAPK3 (0.40) PGR
SCHEMBL13050425 0.76 AKT2 (0.33) HPGDMAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040068059-A1 Aliphatic polyester copolymer and process for producing the same, biodegradable resin molding based on aliphatic polyester, and lactone-containing resin DAICEL CHEMICAL INDUSTRIES LTD. (JP) 2004-04-08 US disclosed
EP-1354908-A1 ALIPHATIC POLYESTER COPOLYMER AND PROCESS FOR PRODUCING THE SAME, BIODEGRADABLE RESIN MOLDING BASED ON ALIPHATIC POLYESTER, AND LACTONE-CONTAINING RESIN DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2003-10-22 EP disclosed
EP-0710684-B1 Preparation process of polyhydroxycarboxylic acid MITSUI CHEMICALS INC (JP) 2001-01-31 EP disclosed
US-5770683-A Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
EP-0710684-A2 Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-05-08 EP disclosed
US-5139885-A Aroamtic polester, halogenated diol, diglycidyl or dicarboxylic acid and a-di-heterocyclic compound; flexible heat stable POLYPLASTICS CO., LTD. (JP) 1992-08-18 US disclosed
US-4954541-A POLYESTER, HALOGENATED COMPOUND, HETEROCYCLIC COMPOUND POLYPLASTICS CO., LTD. (JP) 1990-09-04 US disclosed
EP-0320159-A1 Flame-retardant resin composition and electric wire POLYPLASTICS CO. LTD. (JP) 1989-06-14 EP disclosed
US-4684601-A UNSATURATED, HIGH MOLECULAR WEIGHT DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-08-04 US disclosed
US-4640887-A C,M UNSATURATED POLYESTERS WITH FREE CARBOXY GROUPS; PRINTING DURABLE PLATES WITH IMPROVED OLEOPHILICITY DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-02-03 US disclosed
US-4591545-A Photosensitive image-forming material having a layer of photosensitive polyester modified with chain extender DAINIPPON INK AND CHEMICALS, INC. (JP) 1986-05-27 US disclosed
EP-0019061-B1 PROCESS FOR PRODUCING AROMATIC POLYESTERS HAVING INCREASED DEGREES OF POLYMERIZATION AND MOULDED ARTICLES COMPOSED OF THESE POLYESTERS TEIJIN LIMITED (JP) 1984-08-08 EP disclosed
US-4291152-A CHAIN EXTENSION WITH BICYCLIC OXAZINONE OR OXAZOLONE TEIJIN LIMITED (JP) 1981-09-22 US disclosed
EP-0019061-A1 Process for producing aromatic polyesters having increased degrees of polymerization and moulded articles composed of these polyesters TEIJIN LIMITED (JP) 1980-11-26 EP disclosed