Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP1 | O94782 | 1/20 | 0.36 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135895 | 0.89 | NPC1 (0.33) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6699746 | 0.86 | NPC1 (0.35) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL11126769 | 0.81 | ALOX15 (0.42) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| Gamma-Aminobutyric Acid SCHEMBL5795191 | 0.81 | HDAC3 (0.41) | SMN1; SMN2KMT2AMAPTMEN1GABRA1 | |
| SCHEMBL10448205 | 0.80 | NPC1 (0.45) | SMN1; SMN2NPC1RAB9AKMT2AGAA | |
| SCHEMBL17512909 | 0.80 | USP1 (0.37) | SMN1; SMN2NPC1RAB9AGAAUSP1 | |
| SCHEMBL8915564 | 0.80 | NOTUM (0.44) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL6699184 | 0.79 | ALOX15 (0.41) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL16516875 | 0.78 | KMT2A (0.43) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL5855957 | 0.78 | GSTP1 (0.46) | SMN1; SMN2KMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 937 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120252-B | Preparation method of ramipril key intermediate derivative | 浙江工业大学 | 2024-10-29 | — | — | CN | claimed |
| CN-116120252-A | Preparation method of ramipril key intermediate derivative | 浙江工业大学 | 2023-05-16 | — | — | CN | claimed |
| CN-109320554-B | Novel method for synthesizing practical acetaminoacrylate compound | 浙江海翔药业股份有限公司 | 2021-04-27 | — | — | CN | claimed |
| US-20160102065-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2016-04-14 | — | — | US | claimed |
| US-6461810-B1 | DIAGNOSING GENETIC DISORDERS; GENETIC ENGINEERING | PRINCETON UNIVERSITY | 2002-10-08 | — | — | US | claimed |
| WO-2002004020-A2 | PATHOGEN RESISTANCE IN ORGANISMS | MPB COLOGNE GMBH (DE) | 2002-01-17 | — | — | WO | claimed |
| US-5911987-A | NEWCASTLE DISEASE VIRUS | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) | 1999-06-15 | — | — | US | claimed |
| WO-1999024622-A1 | TRIPLEX IN-SITU HYBRIDIZATION | PRINCETON UNIVERSITY (US) | 1999-05-20 | — | — | WO | claimed |
| EP-0832286-A4 | MODIFIED NUCLEOTIDES FOR NUCLEIC ACID LABELING | ONCOR INC (US) | 1998-11-04 | — | — | EP | claimed |
| EP-0832286-A1 | MODIFIED NUCLEOTIDES FOR NUCLEIC ACID LABELING | ONCOR, INC. (US) | 1998-04-01 | — | — | EP | claimed |
| EP-0223177-B1 | CARDIOTONIC PHENYL OXAZOLONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-08-19 | — | — | EP | claimed |
| EP-0282669-B1 | HERBICIDAL 1,5-DIPHENYL-1H-1, 2,4-TRIAZOLE-3-CARBOXAMIDE DERIVATIVES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-01 | — | — | EP | claimed |
| EP-0282303-B1 | 1,5-DIPHENYL-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-01-15 | — | — | EP | claimed |
| EP-0367233-A2 | Process for the preparation of 2-(2-thienyl)-ethylamine and derivatives thereof | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-05-09 | — | — | EP | claimed |
| US-4874876-A | ACYLATING THIOPHENE, REDUCING, HYDROLYZING | OCCIDENTAL CHEMICAL CORPORATION (US) | 1989-10-17 | — | — | US | claimed |
| EP-0310555-A1 | Derivatives of 1,5-diphenyl-1,2,4-triazole-3-carboxylic acid for crop protection against the phytotoxic activity of herbicides | CIBA-GEIGY AG (CH) | 1989-04-05 | — | — | EP | claimed |
| EP-0297734-A2 | A derivative of 1,5-diphenyl-1H-1,2,4-triazole-3-carboxamide, herbicidal compositions containing the derivative and process for producing the derivative | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-01-04 | — | — | EP | claimed |
| EP-0282669-A1 | Herbicidal 1,5-diphenyl-1H-1, 2,4-triazole-3-carboxamide derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-09-21 | — | — | EP | claimed |
| EP-0282303-A1 | 1,5-Diphenyl-1H-1,2,4-triazole-3-carboxamide derivatives and herbicidal composition containing the same | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-09-14 | — | — | EP | claimed |
| EP-0220956-A2 | Herbicidal 1,2,4-triazole-3-carboxamides | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-05-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160102065-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PPARG, PPARA, TYR | SMN1; SMN2 3671/4885NPC1 3522/4885RAB9A 3882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.