Methacrylic Acid

Methacrylic Acid

SCHEMBL6700140

C=C(C)C(=O)O.C=C(C)C(=O)O.CCOC(=O)NC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.40
TSHR P16473 3/20 0.38
NPC1 O15118 1/20 0.38
KMT2A Q03164 6/20 0.36
GAA P10253 2/20 0.36
HPGD P15428 2/20 0.35
ALDH1A1 P00352 1/20 0.34
MEN1 O00255 2/20 0.33
THRB P10828 2/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
MAPK1 P28482 1/20 0.33
POLB P06746 1/20 0.33
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL534478 1.00 KDM4E (0.40) KDM4ETSHRNPC1KMT2AGAA
Methacrylic Acid SCHEMBL28556599 0.76 GAA (0.40) KDM4ETSHRNPC1KMT2AGAA
Methacrylic Acid SCHEMBL31316646 0.75 THRB (0.50) ALDH1A1THRB
Perflexane SCHEMBL28384308 0.74 THRB (0.48) KDM4ETSHRKMT2AGAAALDH1A1
SCHEMBL31553186 0.74 THRB (0.48) KDM4ETSHRKMT2AGAAALDH1A1
Methacrylic Acid SCHEMBL10521816 0.73 THRB (0.38) KDM4EKMT2AALDH1A1THRBMAPT
Perflubutane SCHEMBL5248074 0.73 THRB (0.46) ALDH1A1THRB
Methacrylic Acid SCHEMBL8846623 0.72 ALDH1A1 (0.33) KDM4ETSHRKMT2AALDH1A1THRB
SCHEMBL9056500 0.72 THRB (0.35) THRB
Methacrylic Acid SCHEMBL28036778 0.71 THRB (0.43) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040006188-A1 Fluorinated acrylate derivatives having carbonate groups and polymerizable composition comprising same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLGY (KR) 2004-01-08 US disclosed