Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580899 | 0.98 | THRB (0.32) | THRB | |
| SCHEMBL28533180 | 0.79 | THRB (0.41) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL2829462 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL27898519 | 0.74 | ALDH1A1 (0.38) | — | |
| Methacrylic Acid SCHEMBL31316646 | 0.73 | THRB (0.50) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL2828712 | 0.73 | ALDH1A1 (0.36) | — | |
| Methacrylic Acid SCHEMBL6700140 | 0.72 | KDM4E (0.40) | THRB | |
| SCHEMBL2828941 | 0.72 | POLB (0.36) | — | |
| SCHEMBL12200560 | 0.72 | CA2 (0.41) | THRBCA2 | |
| Perflubutane SCHEMBL5248074 | 0.71 | THRB (0.46) | THRBCA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425436-B1 | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof | CIBA GEIGY AG (CH) | 1996-12-27 | — | — | EP | disclosed |
| EP-0493320-B1 | Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof | CIBA GEIGY AG (CH) | 1996-07-31 | — | — | EP | disclosed |
| EP-0406161-B1 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA GEIGY AG (CH) | 1995-02-22 | — | — | EP | disclosed |
| US-5334681-A | High oxygen permeability; resiliency, flexibility; wettability; biocompatibility | CIBA-GEIGY CORPORATION (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0493320-A2 | Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |
| US-5115056-A | FLUORINE AND/OR SILICONE CONTAINING POLY(ALKYLENE-OXIDE)-BLOCK COPOLYMERS AND CONTACT LENSES THEREOF | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | disclosed |
| US-5079319-A | Contact Lenses | CIBA-GEIGY CORPORATION (US) | 1992-01-07 | — | — | US | disclosed |
| EP-0425436-A2 | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof | CIBA-GEIGY AG (CH) | 1991-05-02 | — | — | EP | disclosed |
| US-5010141-A | Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | disclosed |
| EP-0406161-A2 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |