Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.32 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HK1 | P19367 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704936 | 0.82 | MAPT (0.44) | ALDH1A1HSD17B10MAPTPOLBKDM4E | |
| SCHEMBL6703975 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HPGDNPSR1HSD17B10MAPT | |
| SCHEMBL6700835 | 0.79 | MAPT (0.40) | NPSR1MAPTPOLBSMN1; SMN2RAB9A | |
| SCHEMBL6702995 | 0.74 | HSD17B10 (0.42) | ALDH1A1HSD17B10MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL6699798 | 0.74 | ALDH1A1 (0.51) | ALDH1A1HPGDNPSR1HSD17B10MAPT | |
| SCHEMBL7681737 | 0.71 | KDM4E (0.42) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7683854 | 0.68 | CACNA1B (0.39) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6704684 | 0.68 | MAPT (0.51) | ALDH1A1HPGDNPSR1HSD17B10MAPT | |
| SCHEMBL26581456 | 0.65 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL14198913 | 0.64 | ALDH1A1 (0.41) | ALDH1A1HPGDNPSR1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |