Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703128 | 0.84 | GPR35 (0.47) | MAPTLMNATP53GAAL3MBTL1 | |
| SCHEMBL6700565 | 0.79 | ALDH1A1 (0.37) | MAPTLMNATP53L3MBTL1NPSR1 | |
| SCHEMBL6703954 | 0.72 | CCR2 (0.47) | MAPTTP53GAAF10LOXL2 | |
| SCHEMBL17993528 | 0.66 | LOXL2 (0.56) | MAPTLMNARAB9AMEN1KMT2A | |
| SCHEMBL17429664 | 0.64 | CYP4A11 (0.60) | MAPTTP53GAARAB9AMEN1 | |
| SCHEMBL2480992 | 0.63 | CCR2 (0.71) | MAPTDRD2TBXA2RF10KMT2A | |
| SCHEMBL5585562 | 0.63 | LOXL2 (0.59) | MAPTLMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL12472344 | 0.63 | HDAC6 (0.73) | MAPTTP53GAARAB9ADRD2 | |
| SCHEMBL9339846 | 0.62 | CYP4A11 (0.62) | MAPTLMNATP53GAAL3MBTL1 | |
| SCHEMBL9339781 | 0.62 | CYP4A11 (0.65) | MAPTLMNATP53GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |