Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704936 | 0.87 | MAPT (0.44) | ALDH1A1KDM4EHSD17B10L3MBTL1MAPT | |
| SCHEMBL6703464 | 0.82 | KDM4E (0.62) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL6702995 | 0.77 | HSD17B10 (0.42) | ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL6717869 | 0.76 | MAPT (0.55) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL7090816 | 0.75 | L3MBTL1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL8366395 | 0.73 | MAPT (0.52) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL28044292 | 0.72 | KDM4E (0.67) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL3952568 | 0.71 | HSD17B10 (0.56) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8687313 | 0.69 | L3MBTL1 (0.65) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL7087440 | 0.69 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10SMN1; SMN2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |