Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HK1 | P19367 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703577 | 0.82 | HSD17B10 (0.48) | HSD17B10MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL6704936 | 0.81 | MAPT (0.44) | HSD17B10MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL6704684 | 0.80 | MAPT (0.51) | HSD17B10MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL6699798 | 0.77 | ALDH1A1 (0.51) | HSD17B10MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL6700565 | 0.74 | ALDH1A1 (0.37) | HSD17B10MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL13100003 | 0.71 | KDM4E (0.48) | HSD17B10MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL5439906 | 0.70 | MAPT (0.46) | HSD17B10MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL6271993 | 0.65 | MAPT (0.48) | HSD17B10MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL28795369 | 0.65 | KDM4E (0.49) | HSD17B10MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL6703408 | 0.64 | MAPT (0.58) | HSD17B10MAPTALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |