Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 8/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77329 | 0.97 | SMAD3 (0.47) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL5142280 | 0.86 | ALDH1A1 (0.50) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL5148271 | 0.85 | ALDH1A1 (0.59) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL202609 | 0.82 | ALDH1A1 (0.50) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL1032008 | 0.81 | ALDH1A1 (0.59) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL7095947 | 0.80 | ALDH1A1 (0.50) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL30887311 | 0.78 | ALDH1A1 (0.63) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL134733 | 0.78 | ALDH1A1 (0.63) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL30887310 | 0.78 | ALDH1A1 (0.63) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL29361906 | 0.78 | ALDH1A1 (0.63) | HPGDALDH1A1BRCA1HSD17B10ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996006190-A9 | COUPLED AMPLIFICATION AND LIGATION METHOD | — | 1996-06-13 | — | — | WO | claimed |
| US-20040054195-A1 | Fluorescent dyes; photostability; labels, staining; analysis | NORTHEASTERN UNIVERSITY | 2004-03-18 | — | — | US | disclosed |
| EP-1274837-A2 | APPARATUS AND METHOD FOR SEPARATING AND PURIFYING POLYNUCLEOTIDES | TRANSGENOMIC, Inc. (US) | 2003-01-15 | — | — | EP | disclosed |
| WO-2002055512-A1 | XANTHENE DERIVATIVES | NORTHEASTERN UNIVERSITY (US) | 2002-07-18 | — | — | WO | disclosed |
| WO-2001081566-A2 | APPARATUS AND METHOD FOR SEPARATING AND PURIFYING POLYNUCLEOTIDES | TRANSGENOMIC, INC. (US) | 2001-11-01 | — | — | WO | disclosed |
| EP-0658167-A1 | 4,7-DICHLOROFLUORESCEIN DYES AS MOLECULAR PROBES | THE PERKIN-ELMER CORPORATION (US) | 1995-06-21 | — | — | EP | disclosed |
| WO-1994005688-A1 | 4,7-DICHLOROFLUORESCEIN DYES AS MOLECULAR PROBES | APPLIED BIOSYSTEMS, INC. (US) | 1994-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054195-A1 | Fluorescent dyes; photostability; labels, staining; analysis | ANXA5, XDH, TFEB | HPGD 472/4885ALDH1A1 2790/4885BRCA1 3563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.