Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL28439560 | 0.81 | CYP2A6 (0.59) | KDM4EMEN1KMT2AGAACYP2C9 | |
| Benzaldehyde SCHEMBL11862136 | 0.81 | ALDH1A1 (0.56) | KDM4EMEN1KMT2AGAACYP2C9 | |
| Morpholine SCHEMBL28295537 | 0.79 | EGFR (0.38) | KDM4EMEN1KMT2AGAACYP2C9 | |
| Anisaldehyde SCHEMBL28293798 | 0.77 | ALDH1A1 (0.63) | KDM4EALDH1A1ALDH1A3CYP2A6 | |
| SCHEMBL28226740 | 0.77 | CYP2A6 (0.52) | KDM4EMEN1KMT2AALDH1A1ALDH3A1 | |
| SCHEMBL28553043 | 0.77 | CYP2A6 (0.52) | KDM4EMEN1KMT2AALDH1A1ALDH3A1 | |
| SCHEMBL214899 | 0.77 | — | — | |
| SCHEMBL28362581 | 0.75 | CYP2A6 (0.50) | KDM4EMEN1KMT2AALDH1A1ALDH3A1 | |
| Hydrochloric Acid SCHEMBL28738883 | 0.75 | CYP2A6 (0.50) | KDM4EMEN1KMT2AALDH1A1ALDH3A1 | |
| SCHEMBL27952608 | 0.75 | CYP2A6 (0.50) | KDM4EMEN1KMT2AALDH1A1ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110745-A1 | Therapeutic chroman compounds | INTEL CORPORATION | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110745-A1 | Therapeutic chroman compounds | HTR1A, ACHE, CALCA | KDM4E 1843/4885MEN1 143/4885KMT2A 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.