Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301040 | 0.76 | KMT2A (0.44) | ALDH1A1TP53CYP3A4KEAP1METAP2 | |
| SCHEMBL6740306 | 0.75 | MEN1 (0.49) | ALDH1A1TP53CYP3A4METAP2MEN1 | |
| SCHEMBL30165333 | 0.67 | ALDH1A1 (0.56) | ALDH1A1TP53CYP3A4TDP1KEAP1 | |
| SCHEMBL9324607 | 0.67 | METAP2 (0.44) | ALDH1A1TP53CYP3A4TDP1KEAP1 | |
| SCHEMBL118567 | 0.67 | KMT2A (0.64) | ALDH1A1TP53CYP3A4TDP1MEN1 | |
| SCHEMBL9159421 | 0.65 | ALDH1A1 (0.53) | ALDH1A1TP53CYP3A4TDP1KEAP1 | |
| Benzidine SCHEMBL29021 | 0.64 | CYP3A4 (1.00) | ALDH1A1TP53CYP3A4TDP1MEN1 | |
| SCHEMBL2024128 | 0.64 | CYP3A4 (1.00) | ALDH1A1TP53CYP3A4TDP1MEN1 | |
| SCHEMBL28842081 | 0.64 | CYP3A4 (1.00) | ALDH1A1TP53CYP3A4TDP1MEN1 | |
| SCHEMBL258287 | 0.64 | CYP3A4 (1.00) | ALDH1A1TP53CYP3A4TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186132-A1 | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186132-A1 | Steroid receptor modulator compounds and methods | NR5A1, ESRRA, NR3C2 | ALDH1A1 3161/4885TP53 3792/4885CYP3A4 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.