Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28168111 | 0.80 | ALDH1A1 (0.55) | RAB9ANPC1CYP2A6ALDH1A1CYP3A4 | |
| SCHEMBL27720890 | 0.76 | MAPT (0.46) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL6806970 | 0.76 | KMT2A (0.50) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL14754412 | 0.76 | CYP19A1 (0.44) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL6734427 | 0.76 | CYP2A6 (0.54) | RAB9ANPC1SMN1; SMN2CYP2E1CYP2A6 | |
| SCHEMBL3618672 | 0.74 | CYP1A2 (0.56) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL8488514 | 0.74 | — | — | |
| SCHEMBL3725904 | 0.74 | KDM4E (0.50) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL6740306 | 0.74 | MEN1 (0.49) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL11830124 | 0.72 | ALDH1A1 (0.38) | CYP2A6ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112552257-A | 3, 5-disubstituted isothiazole compound and synthesis method and application thereof | 五邑大学 | 2021-03-26 | — | — | CN | claimed |
| CN-101230248-A | Sealing strip using epdm rubber as host material | DANYANG WANBEN AUTOMOTIVE PART (CN) | 2008-07-30 | — | — | CN | claimed |
| EP-1592801-A4 | TANDEM ANALYSES OF NONCOVALENTLY DRIVEN EFFECTORS FOR MODULATORY MAPPING OF ACTIVITIES OF PROTEIN SITES | ADVANCED PROTEOME THERAPEUTICS (US) | 2008-04-30 | — | — | EP | claimed |
| EP-1592801-A2 | TANDEM ANALYSES OF NONCOVALENTLY DRIVEN EFFECTORS FOR MODULATORY MAPPING OF ACTIVITIES OF PROTEIN SITES | Advanced Proteome Therapeutics Inc. (US) | 2005-11-09 | — | — | EP | claimed |
| WO-2004066917-A2 | TANDEM ANALYSES OF NONCOVALENTLY DRIVEN EFFECTORS FOR MODULATORY MAPPING OF ACTIVITIES OF PROTEIN SITES | ADVANCED PROTEOME THERAPEUTICS, INC (US) | 2004-08-12 | — | — | WO | claimed |
| CN-1139671-A | 4-alkylsulfur pyrimidine-5-acetous derivant | SANDOZ LTD (CH) | 1997-01-08 | — | — | CN | claimed |
| JP-6211815-A | — | — | None | — | — | JP | disclosed |
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-116063241-B | Synthesis process of 5-bromo-3-phenylisothiazole | 上海予君生物科技发展有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118903118-A | Use of 3-substituted naphtho [2,3-b ] isoxazole-4, 9-dione derivatives for anti-psoriasis | 中南大学 | 2024-11-08 | — | — | CN | disclosed |
| US-20230167103-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-01 | — | — | US | disclosed |
| CN-116063241-A | Synthesis process of 5-bromo-3-phenylisothiazole | 上海予君生物科技发展有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-112159364-B | Synthetic method of isothiazole derivative | 温州大学 | 2022-06-24 | — | — | CN | disclosed |
| EP-0578477-A1 | Treatment of inflammatory bowel disease | ELI LILLY AND COMPANY (US) | 1994-01-12 | — | — | EP | disclosed |
| CN-1049660-A | Aminoketone derivative and application thereof | MITZUI TOATSU CHEMICALS INC (JP) | 1991-03-06 | — | — | CN | disclosed |
| EP-0414391-A2 | Aminoketone derivatives and use thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4544752-A | TREATMENT OF GOUT; ANTIARTHRITIC AGENTS | ELI LILLY AND COMPANY (US) | 1985-10-01 | — | — | US | disclosed |
| EP-0048615-B1 | IMPROVEMENTS IN OR RELATING TO 3-ARYL-5-ISOTHIAZOLE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-05-30 | — | — | EP | disclosed |
| US-4346094-A | ENZYME INHIBITORS | ELI LILLY AND COMPANY (US) | 1982-08-24 | — | — | US | disclosed |
| EP-0048615-A1 | Improvements in or relating to 3-aryl-5-isothiazole derivatives | ELI LILLY AND COMPANY (US) | 1982-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167103-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | DGKZ, DGKA, DGKG | KMT2A 1166/4885RAB9A 949/4885MEN1 4290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.