Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.41 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695878 | 0.90 | SIGMAR1 (0.58) | SIGMAR1CCR3EPHX1EPHX2NPFFR1 | |
| SCHEMBL6702012 | 0.89 | DRD4 (0.52) | SIGMAR1NPFFR1NPFFR2MCHR1ACHE | |
| SCHEMBL6702833 | 0.89 | KMT2A (0.51) | SIGMAR1CCR3EPHX2 | |
| SCHEMBL6703098 | 0.88 | KMT2A (0.50) | SIGMAR1CCR3FAAHACHE | |
| SCHEMBL6700051 | 0.86 | DRD4 (0.54) | SIGMAR1CCR3FAAHACHE | |
| SCHEMBL6698789 | 0.85 | ACHE (0.51) | SIGMAR1FAAHACHEBCHE | |
| SCHEMBL6699771 | 0.85 | SIGMAR1 (0.46) | SIGMAR1CCR3FAAH | |
| SCHEMBL6702902 | 0.85 | MAPT (0.57) | SIGMAR1 | |
| SCHEMBL6704083 | 0.84 | EPHX2 (0.47) | SIGMAR1EPHX2ACHE | |
| SCHEMBL6708092 | 0.84 | KMT2A (0.47) | SIGMAR1EPHX1EPHX2NPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044037-A1 | Amidino-urea serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their snythesis | HONG YUFENG (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044037-A1 | Amidino-urea serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their snythesis | HTR7, HTR1A, HTR2C | RAB9A 1043/4885SIGMAR1 22/4885PRKAA2 3289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.