Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6095134 | 1.00 | HRH3 (0.42) | HRH3TLR7TLR8NUDT1SIGMAR1 | |
| SCHEMBL6288252 | 0.87 | EPHX2 (0.47) | HRH3 | |
| SCHEMBL6773368 | 0.86 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL6773840 | 0.85 | TLR7 (0.37) | TLR7TLR8NUDT1 | |
| SCHEMBL6777299 | 0.85 | ALDH1A1 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL6768386 | 0.85 | TLR7 (0.42) | TLR7TLR8NUDT1 | |
| SCHEMBL6279887 | 0.84 | TLR7 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL6773457 | 0.84 | L3MBTL1 (0.42) | TLR7TLR8NUDT1 | |
| SCHEMBL6897348 | 0.84 | ALDH1A1 (0.46) | TLR7TLR8NUDT1 | |
| SCHEMBL6774067 | 0.83 | ALDH1A1 (0.39) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186128-A1 | Amide substituted imidazopyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186128-A1 | Amide substituted imidazopyridines | IRF3, EIF2AK2, IFNG | HRH3 287/4885TLR7 75/4885TLR8 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.