SCHEMBL6701301

SCHEMBL6701301

COc1ccc(C(=O)O)c(-c2ccccc2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.63
AKR1C3 P42330 5/20 0.56
AKR1C2 P52895 5/20 0.56
BACE1 P56817 3/20 0.54
HDAC8 Q9BY41 2/20 0.52
ALDH1A1 P00352 2/20 0.51
LMNA P02545 1/20 0.51
CYP1A2 P05177 1/20 0.51
PGR P06401 1/20 0.51
CYP2D6 P10635 1/20 0.51
HPGD P15428 1/20 0.51
SLC6A2 P23975 1/20 0.51
PDE4A P27815 1/20 0.51
MAPK1 P28482 1/20 0.51
CYP2C19 P33261 1/20 0.51
HRH1 P35367 1/20 0.51
HTT P42858 1/20 0.51
SLC6A3 Q01959 1/20 0.51
PDE4D Q08499 1/20 0.51
POLB P06746 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7591657 0.91 SMN1; SMN2 (0.75) SMN1; SMN2AKR1C3AKR1C2BACE1ALDH1A1
Acrylic Acid SCHEMBL27869593 0.91 SMN1; SMN2 (0.54) SMN1; SMN2AKR1C3AKR1C2BACE1HDAC8
SCHEMBL8202718 0.90 PRKAB2 (0.55) SMN1; SMN2AKR1C3AKR1C2ALDH1A1LMNA
SCHEMBL8782870 0.90 CYP1A2 (0.57) SMN1; SMN2AKR1C3AKR1C2BACE1HDAC8
SCHEMBL22319299 0.88 ALDH1A1 (0.57) SMN1; SMN2AKR1C3AKR1C2BACE1HDAC8
SCHEMBL9683222 0.87 SMN1; SMN2 (0.64) SMN1; SMN2AKR1C3AKR1C2BACE1ALDH1A1
SCHEMBL9151080 0.87 SMN1; SMN2 (0.64) SMN1; SMN2AKR1C3AKR1C2ALDH1A1CYP1A2
SCHEMBL8566031 0.87 SMN1; SMN2 (0.64) SMN1; SMN2AKR1C3AKR1C2ALDH1A1CYP1A2
SCHEMBL6775841 0.87 KDM4E (0.62) SMN1; SMN2AKR1C3AKR1C2BACE1HDAC8
SCHEMBL5342329 0.86 SMN1; SMN2 (0.84) SMN1; SMN2AKR1C3AKR1C2BACE1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118712660-A High-porosity dry-method diaphragm for lithium ion battery and preparation method thereof 宁波长阳科技股份有限公司 2024-09-27 CN claimed
US-6552022-B1 Atherosclerosis in a mammal, pancreatitis, non-insulin dependent diabetes mellitus, coronary heart disease in a lowering serum lipid levels SMITHKLINE BEECHAM CORPORATION 2003-04-22 US claimed
EP-1135378-A1 BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 SECRETION INHIBITORS GLAXO GROUP LIMITED (GB) 2001-09-26 EP claimed
WO-2000032582-A1 BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 SECRETION INHIBITORS GLAXO GROUP LIMITED (GB) 2000-06-08 WO claimed
US-20250302861-A1 SMALL RNA AND USE THEREOF IN TREATMENT OF HYPERLIPIDEMIA BEIJING BAISHIHEKANG PHARMACEUTICAL TECHNOLOGY (BSJPHARMA) CO., LTD (CN) 2025-10-02 US disclosed
CN-118712660-B High-porosity dry-method diaphragm for lithium ion battery and preparation method thereof 宁波长阳科技股份有限公司 2025-02-11 CN disclosed
CN-118712660-B High-porosity dry-method diaphragm for lithium ion battery and preparation method thereof 宁波长阳科技股份有限公司 2025-02-11 CN disclosed
EP-4471145-A1 SMALL RNA AND USE THEREOF IN TREATMENT OF HYPERLIPIDEMIA Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CN) 2024-12-04 EP disclosed
CN-118712660-A High-porosity dry-method diaphragm for lithium ion battery and preparation method thereof 宁波长阳科技股份有限公司 2024-09-27 CN disclosed
CN-118712660-A High-porosity dry-method diaphragm for lithium ion battery and preparation method thereof 宁波长阳科技股份有限公司 2024-09-27 CN disclosed
US-12059467-B2 Low-toxicity and high-efficiency orthoester mixture pharmaceutical adjuvant, preparation method thereof, and topical sustained release drug delivery formulation including same ANHUI UNIVERSITY (CN) 2024-08-13 US disclosed
US-20240108728-A1 IMPROVED LOW-TOXICITY AND HIGH-EFFICIENCY ORTHOESTER MIXTURE PHARMACEUTICAL ADJUVANT, PREPARATION METHOD THEREOF, AND TOPICAL SUSTAINED RELEASE DRUG DELIVERY FORMULATION INCLUDING SAME ANHUI UNIVERSITY (CN) 2024-04-04 US disclosed
WO-2000032582-A1 BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 SECRETION INHIBITORS GLAXO GROUP LIMITED (GB) 2000-06-08 WO disclosed
EP-0897903-A2 Ketone-derivatives of indene, dihydronaphthalene or naphthalene compounds for the treatment of hyperlipidemia ELI LILLY AND COMPANY (US) 1999-02-24 EP disclosed
WO-1999007360-A1 COMPOUNDS AND USES THEREOF ELI LILLY AND COMPANY (US) 1999-02-18 WO disclosed
EP-0352578-A2 Method of making thin anisotropic films on carriers with structured surfaces Röhm GmbH (DE) 1990-01-31 EP disclosed
EP-0057503-B1 PRODUCTION OF HYDROXY ARYLOPHENONES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-03-20 EP disclosed
US-4453010-A Production of hydroxy arylophenones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-06-05 US disclosed
EP-0057503-A1 Production of hydroxy arylophenones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-08-11 EP disclosed
US-4339560-A Process for polymerizing olefins SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108728-A1 IMPROVED LOW-TOXICITY AND HIGH-EFFICIENCY ORTHOESTER MIXTURE PHARMACEUTICAL ADJUVANT, PREPARATION METHOD THEREOF, AND TOPICAL SUSTAINED RELEASE DRUG DELIVERY FORMULATION INCLUDING SAME TLR7, PON1, MYD88 SMN1; SMN2 412/4885AKR1C3 3143/4885AKR1C2 3079/4885
US-12059467-B2 Low-toxicity and high-efficiency orthoester mixture pharmaceutical adjuvant, preparation method thereof, and topical sustained release drug delivery formulation including same TLR7, PON1, MYD88 SMN1; SMN2 395/4885AKR1C3 3550/4885AKR1C2 3448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.