Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 3/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.35 |
| ▸ | LATS1 | O95835 | 2/20 | 0.35 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.35 |
| ▸ | IL1B | P01584 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19122592 | 0.88 | NUDT1 (0.44) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL6700003 | 0.78 | MAPT (0.44) | ALDH1A1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL12332403 | 0.78 | HCAR3 (0.50) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL18745774 | 0.77 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL1435912 | 0.77 | NPC1 (0.46) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL6700607 | 0.77 | PTK2 (0.45) | ALDH1A1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL12212102 | 0.77 | NUDT1 (0.39) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17658883 | 0.76 | HCAR3 (0.57) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL18266146 | 0.75 | PDE2A (0.39) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL3827086 | 0.74 | RAB9A (0.51) | ALDH1A1NPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | ALDH1A1 925/4885NPC1 700/4885RAB9A 2032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.