Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702824 | 0.84 | KIF11 (0.53) | AKR1C3MAPTKMT2ATDP1KDM4E | |
| SCHEMBL6704097 | 0.84 | KIF11 (0.53) | AKR1C3MAPTKMT2ATDP1KDM4E | |
| SCHEMBL6703729 | 0.83 | PARP1 (0.42) | MAPTKMT2ATDP1KDM4EGAA | |
| SCHEMBL6702073 | 0.83 | RAD51 (0.49) | AKR1C3MAPTKMT2AKDM4EGAA | |
| SCHEMBL6699022 | 0.83 | KIF11 (0.54) | MAPTKMT2ATDP1KDM4EGAA | |
| SCHEMBL6703556 | 0.83 | MAPT (0.46) | AKR1C3MAPTKMT2ATDP1KDM4E | |
| SCHEMBL6705448 | 0.81 | ALDH1A1 (0.42) | MAPTKMT2ATDP1KDM4EGAA | |
| SCHEMBL6703990 | 0.81 | ALDH1A1 (0.51) | AKR1C3MAPTKMT2AKDM4EGAA | |
| SCHEMBL6699680 | 0.79 | ALDH1A1 (0.54) | MAPTKMT2AGAAALDH1A1MEN1 | |
| SCHEMBL6704507 | 0.79 | ALDH1A1 (0.46) | MAPTKMT2AKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116417-A1 | Thiohydantoins and use thereof for treating diabetes | LABORATOIRES FOURNIER SA (FR) | 2004-06-17 | — | — | US | disclosed |