Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | GAA | P10253 | 7/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 3/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LGMN | Q99538 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704097 | 0.89 | KIF11 (0.53) | PARP1KIF11MAPTALDH1A1GAA | |
| SCHEMBL6702824 | 0.89 | KIF11 (0.53) | PARP1KIF11MAPTALDH1A1GAA | |
| SCHEMBL6699022 | 0.88 | KIF11 (0.54) | PARP1KIF11MAPTALDH1A1GAA | |
| SCHEMBL6703556 | 0.88 | MAPT (0.46) | PARP1KIF11MAPTALDH1A1GAA | |
| SCHEMBL6702073 | 0.88 | RAD51 (0.49) | PARP1KIF11MAPTALDH1A1GAA | |
| SCHEMBL6703990 | 0.85 | ALDH1A1 (0.51) | MAPTALDH1A1GAAALOX12KDM4E | |
| SCHEMBL6705448 | 0.85 | ALDH1A1 (0.42) | PARP1KIF11MAPTALDH1A1GAA | |
| SCHEMBL6704313 | 0.83 | AKR1C3 (0.50) | MAPTALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL6699680 | 0.82 | ALDH1A1 (0.54) | MAPTALDH1A1GAAALOX12KMT2A | |
| SCHEMBL6704507 | 0.82 | ALDH1A1 (0.46) | KIF11MAPTALDH1A1GAAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116417-A1 | Thiohydantoins and use thereof for treating diabetes | LABORATOIRES FOURNIER SA (FR) | 2004-06-17 | — | — | US | disclosed |