Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 7/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PLTP | P55058 | 2/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682217 | 0.92 | TRPV4 (0.38) | TRPV4MEN1CCKARKMT2AMAPT | |
| SCHEMBL7679717 | 0.91 | MEN1 (0.40) | TRPV4MEN1CCKARKMT2AMAPT | |
| SCHEMBL6703565 | 0.87 | TRPV4 (0.35) | TRPV4SCDKMT2AMAPTALDH1A1 | |
| SCHEMBL7086912 | 0.86 | SCD (0.36) | TRPV4SCDMEN1CCKARKMT2A | |
| SCHEMBL7684903 | 0.86 | KMT2A (0.42) | TRPV4MEN1CCKARKMT2APLTP | |
| SCHEMBL7688740 | 0.85 | MEN1 (0.46) | TRPV4MEN1CCKARKMT2AMAPT | |
| SCHEMBL7677660 | 0.85 | TRPV4 (0.37) | TRPV4MEN1CCKARKMT2APLTP | |
| SCHEMBL7086907 | 0.84 | F10 (0.38) | TRPV4SCDMEN1CCKARKMT2A | |
| SCHEMBL7688497 | 0.84 | MEN1 (0.39) | TRPV4MEN1CCKARKMT2AMAPT | |
| SCHEMBL6702441 | 0.83 | MAPT (0.39) | TRPV4MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| EP-1301482-A1 | CYCLIC AMINE PHENYL BETA-3 ADRENERGIC RECEPTOR AGONISTS | Wyeth (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |
| WO-2002006232-A1 | CYCLIC AMINE PHENYL BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |