Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 9/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701625 | 0.81 | ALDH1A1 (0.59) | KDM4ECRHBPCRHR2SMN1; SMN2CNR2 | |
| SCHEMBL15622413 | 0.81 | KDM4E (0.68) | KDM4ECRHBPCRHR2SMN1; SMN2CNR2 | |
| SCHEMBL11006782 | 0.77 | TP53 (0.58) | KDM4ECRHBPCRHR2SMN1; SMN2MEN1 | |
| SCHEMBL6702303 | 0.77 | TSHR (0.41) | KDM4ECRHBPCRHR2SMN1; SMN2CNR2 | |
| SCHEMBL7086344 | 0.76 | CNR2 (0.42) | KDM4ECRHBPCRHR2SMN1; SMN2CNR2 | |
| SCHEMBL8693185 | 0.75 | MCL1 (0.58) | KDM4ECRHBPCRHR2SMN1; SMN2CNR2 | |
| SCHEMBL8691611 | 0.74 | MCL1 (0.57) | KDM4ECRHBPCRHR2SMN1; SMN2CNR2 | |
| SCHEMBL8653460 | 0.74 | KDM4E (0.64) | KDM4ECRHBPCRHR2SMN1; SMN2CNR2 | |
| SCHEMBL7686010 | 0.73 | MCL1 (0.56) | KDM4ECRHBPCRHR2SMN1; SMN2CNR2 | |
| SCHEMBL3554973 | 0.71 | HDAC1 (0.60) | SMN1; SMN2MEN1KMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |