Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 6/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701629 | 0.81 | MCL1 (0.50) | TSHRF10NOD2NOD1MEN1 | |
| SCHEMBL6702307 | 0.77 | KDM4E (0.47) | TSHRF10NOD2NOD1CNR2 | |
| SCHEMBL20037197 | 0.77 | MEN1 (0.45) | TSHRNOD2NOD1MEN1KMT2A | |
| SCHEMBL7086344 | 0.74 | CNR2 (0.42) | TSHRF10NOD2NOD1CNR2 | |
| SCHEMBL7684555 | 0.71 | MCL1 (0.53) | TSHRCNR2MEN1KMT2AALDH1A1 | |
| SCHEMBL5794123 | 0.71 | NOD2 (0.57) | TSHRF10NOD2NOD1MEN1 | |
| SCHEMBL29463237 | 0.71 | NOD2 (0.57) | TSHRF10NOD2NOD1MEN1 | |
| SCHEMBL19362902 | 0.68 | KMT2A (0.46) | TSHRCNR2MEN1KMT2AKDM4E | |
| SCHEMBL7682416 | 0.67 | F10 (0.44) | F10NOD2NOD1CNR2MEN1 | |
| SCHEMBL3651263 | 0.66 | NOD2 (0.65) | TSHRF10NOD2NOD1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |