Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.47 |
| ▸ | CCR2 | P41597 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCR9 | P51686 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677561 | 0.85 | GPR35 (0.44) | GPR35CCR2KDM4EALDH1A1CCR9 | |
| SCHEMBL6703456 | 0.83 | GPR35 (0.51) | GPR35CCR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2476665 | 0.79 | CCR2 (0.60) | CCR2KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6703464 | 0.79 | KDM4E (0.62) | CCR2KDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6703975 | 0.78 | ALDH1A1 (0.42) | GPR35CCR2KDM4ESMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9085791 | 0.78 | ALDH1A1 (0.59) | CCR2KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6742117 | 0.78 | GAA (0.51) | GPR35CCR2KDM4EMAPT | |
| SCHEMBL13100002 | 0.77 | KDM4E (0.49) | KDM4ESMN1; SMN2ALDH1A1HSD17B10MAPT | |
| SCHEMBL6703577 | 0.76 | HSD17B10 (0.48) | CCR2KDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL14487798 | 0.70 | ATM (0.52) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |