Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704568 | 0.87 | KIF11 (0.44) | ALDH1A1MAPTHSD17B10POLBAKR1C3 | |
| SCHEMBL6701945 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPTHSD17B10KIF11GAA | |
| SCHEMBL6702824 | 0.84 | KIF11 (0.53) | ALDH1A1MAPTRAD51PKMPOLB | |
| SCHEMBL6704097 | 0.84 | KIF11 (0.53) | ALDH1A1MAPTRAD51PKMPOLB | |
| SCHEMBL6702073 | 0.83 | RAD51 (0.49) | ALDH1A1MAPTRAD51AKR1C3KIF11 | |
| SCHEMBL6704444 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPTHSD17B10PKMPOLB | |
| SCHEMBL6703556 | 0.79 | MAPT (0.46) | ALDH1A1MAPTHSD17B10AKR1C3KIF11 | |
| SCHEMBL6703729 | 0.79 | PARP1 (0.42) | ALDH1A1MAPTHSD17B10POLBTP53 | |
| SCHEMBL6699022 | 0.79 | KIF11 (0.54) | ALDH1A1MAPTHSD17B10POLBKIF11 | |
| SCHEMBL6627356 | 0.78 | MAPT (0.44) | ALDH1A1MAPTHSD17B10RAD51PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116417-A1 | Thiohydantoins and use thereof for treating diabetes | LABORATOIRES FOURNIER SA (FR) | 2004-06-17 | — | — | US | disclosed |