⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4830844 | 0.75 | TSHR (0.31) | — | |
| SCHEMBL4835390 | 0.74 | KDM4E (0.36) | — | |
| SCHEMBL4831351 | 0.73 | — | — | |
| SCHEMBL4833546 | 0.73 | KDR (0.31) | — | |
| SCHEMBL4831187 | 0.71 | MAPT (0.40) | — | |
| SCHEMBL6703099 | 0.69 | NR3C2 (0.32) | — | |
| SCHEMBL4588620 | 0.67 | HTR3E (0.47) | — | |
| SCHEMBL4830870 | 0.66 | PGR (0.43) | — | |
| SCHEMBL4834430 | 0.66 | RAB9A (0.47) | — | |
| SCHEMBL4830984 | 0.66 | EPHX1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425284-A2 | FURO- AND THIENOPYRIMIDINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003022852-A2 | FURO-AND THIENOPYRIMIDINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-03-20 | — | — | WO | disclosed |